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doi: 10.3389/fimmu.2021.781151 41 JacobsonAYangDVellaMChiuIM

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ROS also stabilizes MAPK activation indirectly by inactivating MAPK phosphatases (MKPs): Oxidation of catalytic cysteines prevents their dephosphorylation activity [71], and oxidative stress can induce MKP degradation [72]